Tourette Syndrome
Tourette syndrome is a neurological disorder characterized by repetitive, involuntary movements and vocalizations called tics. Many individuals with Tourette syndrome lead normal lives, with tics often improving or changing in severity as they age.
Cause: The exact cause is unclear, but it is thought to involve a combination of genetic and environmental factors. It is believed to involve abnormalities in the brain areas that control movement.
Features: Tics can be motor (e.g., blinking, head jerking) or vocal (e.g., grunting, throat clearing, swearing). Tics often appear between the ages of 5-10 and can change in type and severity over time.
Diagnosis: Based on clinical symptoms, typically involving the presence of tics for at least one year. No specific test for Tourette syndrome.
Treatment: No cure, but treatment options include behavioral therapy (CBT) to manage tics and medications (e.g., antipsychotics, alpha-agonists) to control severe symptoms.
Active Trials
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Past Trials
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TITLE: A Multicenter, Double-Blind, Placebo-Controlled, Randomized Withdrawal Study to Evaluate the Safety and Maintenance of Efficacy of Ecopipam in Children, Adolescents and Adults with Tourette’s Disorder.
SPONSOR: Emalex Biosciences, Inc.
INDICATION: Tourette’s Syndrome
PROTOCOL: EBS-101-TD-301
PHASE: 3
DESCRIPTION: This Phase 3 multicenter study evaluates the maintenance of efficacy, safety and tolerability of ecopipam tablets in children, adolescents and adults in the treatment of Tourette's Disorder (TD). The study includes an open-label period followed by double-blind, placebo-controlled, randomized withdrawal period.
STATUS: Active
RECRUITING PATIENTS: No
RDR LOCATION: Georgia